Cayenne is famous for reducing many types of pain. It works by effecting your nervous system. Substance P is a neurotransmitter that relays information and results in what we call pain. Capsaicin, a major constituent of cayenne peppers, blocks substance P and therefore reduces pain.
When cayenne is used topically it can relieve many different types of pain, from diabetic neuropathy, shingles, migraine headaches, back aches, arthritis, menstrual cramps and bruises.